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Exercise therapy for idiopathic inflammatory myopathies : ウィキペディア英語版 | Exercise therapy for idiopathic inflammatory myopathies Although they vary in particulars, polymyositis, dermatomyositis and inclusion body myositis are idiopathic inflammatory myopathies (IIM)() primarily characterized by chronic inflammation of human skeletal muscle tissue〔Lundberg I. and Y-L Chung, 2000. Treatment and Investigations of idiopathic inflammatory myopathies. "Rheumatology". 39:7-17.〕 that ultimately causes the necrosis of muscle cells. This degeneration leads to muscle tissue wasting, weakness and fatigue among other serious effects. Until recently, exercise has been avoided as a type of therapy, and even forbidden due to the risk of triggering or amplifying inflammation. However, several studies have been conducted to test this assumption and have shown that aerobic exercise as well as resistance training can maintain and even improve quality of life for IIM-affected individuals without increased inflammatory response.〔Painelli VdS, B Gualano, GG Artioli, AL de Sa Pinto, E Bonfa, AH Lancha Jr., FR Lima, 2009. The possible role of physical exercise on the treatment of idiopathic inflammatory myopathies. ''Autoimmunity Reviews''. 8:355-359.〕 ==Modes of exercise therapy: trials==
With the main goals of treatment being improved functionality and quality of life, exercise programs should focus on “functional” exercises (e.g. walking, walking up/down stairs, sit-to-stand), when applicable. Performing functional exercises increases (a) the efficiency of the exercise program and (b) the likelihood the improvements will be transferred to activities of daily living.〔Johnson, L.G., Collier, K.E., Edwards, D.J., Phillippe, D.L., Eastwood, P.R., Walters, S.E., Thickbroom, G.W., Mastaglia, F.L. (2009). Improvement in aerobic capacity after an exercise program in sporadic inclusion body myositis. Journal of Clinical Neuromuscular Disease, 10(4), 178-184〕
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